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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b76f113ecf2c0392ff467aa9bcb840ae1b5c5700e30281e7fb1f997af94157' 
  AND token = '4g+XAww01YzGzirVjPRwCgpwe8XmFNM8srPRDgvkdXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}