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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34d21a069c42d0aab51132f4a07e143660baa3dcd42972b391c2e2801052f583' 
  AND token = 'u+jomd/oTX+w5tWsz+9b188cXqQy3OjqA+c2g3NWHEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}