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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5167e49e94c394e68e79b9372ed4dfc6861442be1074d1adb07a90585b911050' 
  AND token = 'vphYdH1jHKnm+oWOkycGy1UKL3tdjkqPkYD03ZW2Y/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}