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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1ee0dbe7b63aaa885c106db325e9713ab38b971643ffba70937f5659064430' 
  AND token = 'yVciF+x8VMAbrLpiGofOZLKS1WwM2LfMdu6cjXyWvDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}