SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fee4b3ea8190399aead84575ba568bd629f5c9558b3d59c7fc2dbd09d15da116' 
  AND token = 'EyCIEBWjzpMcJkhFEaScIr2RfllvngE1UI3ChmRB2aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}