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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eff52ad4fd4dd6ba60022b278f8b2c5efa86457c8e697b9d3c73886c19a00ed' 
  AND token = 'H3exMY60AeHp/kOdP7YlAuKfFm4zSh73XHpwK7chi04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}