SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1b05f5da4f9f1d8ab12406142dec06e81859bec65a70fe1fb4bd38c170385f' 
  AND token = '3YVtNctc+Tf4NYsWZdFzfS39jAbJw7FruUjsblFwUdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}