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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5578b88c63e155de1814e434ba164800b621640ab4d2ebd28649917e9f43a2' 
  AND token = 'h4IZ3veF57qH2QCCahkfjvmIzf0FlI6i1cSIJZHcc9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}