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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429cb7d7cf2cc915eba386d2297a6b6a53d41f135b1186a1b0e5b2477c7d2058' 
  AND token = 'kbzyv0vB7Qgu294OHKOWeRg2gNaN9YQ51dfIZqHUbT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}