SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73aa1d2e534ef290736a54bb4d0030ce4966d09eda85c9b378d192f00fd845b3' 
  AND token = 'GXHsffHIuDtK3rJoR4B+3bizpiocsljn4uwN08Q428g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}