SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a72590620b06e2d5eb26654e4567b61606184151a17849d4bf902e2d1435cc6' 
  AND token = 'DxfD7NnQH8WlPT+PdCzbSOL+ogGt4pZnUAdbTFvMIT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}