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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64afa7737f07e50afee43abd4fc74f4993ca5be6a36cf40a86204c288757e4d' 
  AND token = 'VFwLG3O+PrVTDNqEdNiTr+y/7JKT3WY/h2xHKni8IbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}