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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc48aacb2a8210d8f5886a6662bd59d57878054f010312ae7505c2c04bc980da' 
  AND token = '5KYn36NuB/F7s5nx+sMixM/vbmdSUiF3RHVzkgnaGEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}