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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168220c1d737b80501c00d9bbe6ba5f04262b453f0996d955b725c082e87928b' 
  AND token = 'cXtpHzDN0Zin4apR36lkgapPvyUyU2Jn6Ju4Zm0jry4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}