SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd7cc5b89763ceac99bb9c2ec673e05453d51174a443dcbe7e2bceaeaa8b511' 
  AND token = '0OcUwiF08O4tzhI7OwPVPMKXZ1+tJXRFoYPKoon41E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}