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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b9dc2ca66df76999c02569539ed0384d2cb7346e043d83d9b6abeb8bda225a' 
  AND token = 'Tbt/iGIEvTb4Fg1zt2DuFAYNpwm0Oe/37EmXlGrckzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}