SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01659d078105ecdc6f224e5f7628c27e8613c8407056ca969d79496742f78729' 
  AND token = 'Z1gTf3QTsdPlJ7wZfr9UNAO5fJ8DT2XPsBqJfLRHWic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}