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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afa6fa6cf766904e8852189be69ef660e3b6a945c1793d00e0a678e20b97947' 
  AND token = 'x42fJhSSRFJOaO8CJDGwfU57qgFV1IClhse6tCni4Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}