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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c79e89ae11785669208582ff845a1a6dfe9be59ba4e610f20726eb6081caf3' 
  AND token = 'r3yzB3KZsHkuI0wmW/KCA8fMSsDwNhASuLj1D2wp8bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}