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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b8f9512dd3a7b347121bfb80129cb5749998b939381bb7ef50193a279f6320a' 
  AND token = 'CGbk0jGbwu7GFdpPg3PIGyDwlnf/zZSPNgq6Y5pGM0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}