SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcb9fa00b4ce363ac27cdd9ffc431db158e14fdb0e223a1319cf582630213ee' 
  AND token = 'gwbtsgbqDCWmRIFkJ+w4U0aBguf9dThPZeRTz0DMTiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}