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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c1acc391c0d92601b546fa41094c11ef39a8702be4f4ec63d289a42d4627c0' 
  AND token = 'V49Qw+x3PFZBtIDSeM0dc4L581slZKdl+4G2EifSJsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}