SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c05d4672f06282a196e8f67d9fcf70881f1fd7325ec3043847e9bc24c10bb76' 
  AND token = 'AN008j3QdqDenrIQztYhHRrwfkGfXwd2/i5YWm33A/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}