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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d049c7a65299455e10b0426aad4cdfc1caa25dc43c6e28f5fa5b137ecff338' 
  AND token = '8upzH+sjyxZsmCrY4hcwFlnM3ZekrudxoSxibkvJxzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}