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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008ed19c22387b4bdcea7634da8adfbf6ed4ab56f5a4444b6c6504f7526cd7c2' 
  AND token = 'lHFY3vctZ65uu3seav3JlZfUTrJ3DCkM/Tl1TeuG+G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}