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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481afd9aa438dc46c76b2218a497b657ddbe6ab6c9d18e6eaffff15c6bab7070' 
  AND token = 'vPAsJw3Xt4K2hzcw9FXCz3vyBKJ2290wC61afRTo77k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}