SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e05bfb313bb702deb266798b2a99704a8b533012874fb0ce71798ee87aaefe1' 
  AND token = '0drcJ23y0IDdQVVfzAjvMEum+hn/srm2daetwrKfm2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}