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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f20ec8b85016083282ea2817b67104e90a5bcb4a28c8783a0b3b956436f6975' 
  AND token = 'iE8xKW9dgY2jif1o008FDfKmIPROc3fjrgAmY7pfTls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}