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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9feaa811d9a5997960d3c089470a2966f0cc3156f684b8fa15f471df7fd453' 
  AND token = 'SEodoR9qA8CONeo6TXS36VFF7iPOokxesmEY2i6Jj2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}