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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fdd89574866d87add1d8d9b721e3136800658cc359063ee0d2a7fe30b0fe25' 
  AND token = 'RWpkapU17W51XlY4Cjg1j710blLTLmiMKShgYBkYPeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}