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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135286b78599b35dbdc3a47050a7a158cb743ba80a1059e15b84ebaeda0d6111' 
  AND token = 'o3RS6qAcdRAMiQt+VckMOag6uBObCa+odCxwfDQSSk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}