SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75d796e02b3b4e96ef0ce337c7c6735ec3542c78caf5c759d591cc540a25bd79' 
  AND token = '4F6b4X1HVhQGUsUuRJODVrwBbiI9zkDLZmYNoPYECLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}