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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f2f496ca00cf71ce796b036a91e717bb42ef3a0830380d0373e41a80706920' 
  AND token = 'TjWEUDrGM+RtLgbAd8ZWdPBoFwTu9+6p1kHciz7f2F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}