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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c091f7d759079825ff92fcb65c7c50cb1a003c6f0406a383a80b4251280c7626' 
  AND token = 'GQd4hF0m8hkZ1rMOK0YdAoNskgFNrpfaMufkH9B77I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}