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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40944ae6e4f4dc495dd3fa341125d310e5e142be0226447014c43a8334723436' 
  AND token = 'gl1BICK0wYxNkOqQNfZX1SgF0k4QmzjInlxjZRKz4Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}