SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618f2e986296b39728524d672b4643df6e510bab3b2bf8040578aa0d0b9c2066' 
  AND token = 'zj8CQ4BdNBhk0ZprdG98qXLrXLqibkwiCbzLF5W/YHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}