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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468921b3e2eeb03ef6e7de35490498fccf473f5721a36010f98ffbabfcf29d64' 
  AND token = 'u1mQ1zkTM7r1kBiRYUVziZAUVEgyp24KFHKt7uO4Gsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}