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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13708d1ca0ce8e45902c6d3fe49e76fd75effbefe79bf5172439fb25cf68bfdd' 
  AND token = 'M22PXf9Txb7hNIUoIvz/N3Z0KMcVd3/jCLLZrBpQuPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}