SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822d36acbc1a670672d3a1832389600707791ab711752fefa36150fd85b31bf6' 
  AND token = 'tYk2fM7iIqIL4Lt5f1GgVifIcD+Mr+6I5Sc8KakY89Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}