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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a0c81ca20c4a1f174646db4ec3bd7b6293a6788ce44b3c7c4d19e04811038f' 
  AND token = 'laRmkv2P8uhYYTSMB4FwCPlNlg4Up6JUCnjZnJSBUeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}