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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6aff0a13de61af38e226170437232802c5f7a4e73c9ad0172d12eac2197dcd' 
  AND token = 'rODDgk6lSq2gGUwzuQrrhaPxG8XxZ+AhFtWBP6bfL4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}