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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb0f9d2786bb40f59cf7d6f3962ebef2223850f9fc51485c26131da0165d212' 
  AND token = 'GzeDe+ucFllzNQG6mT2MNCoIFl2Kdfvbutj25kR86hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}