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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1623d68d7d8cab6e73d55d63a0e0f1b7b30830068d021e5aacb9ca8a90b11dd1' 
  AND token = 'NFiQRXuz2X59xdVFD4XX8qhJrqCiwXjPuiMTsY5tfao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}