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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a25541dd351261b99a9bd89fc1050ae1bc3fc40506505b9aec0aa0dbb5727a' 
  AND token = 'YOwD/1q4R4CMq1wi0MjZtrAkFR7xefs2wxTD8/aDZbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}