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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4008216101b1bc1d82d3814833c57525a4a1f0da5cbdea5b9c39a53b7add79' 
  AND token = '+PXESXEaQHTJPd49zkJBb6YeBbCexOsN7gk7uggiEkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}