SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ddc503a438e0dca1ce9c8206d2415781044d072d2db3c49fe387442769528d4' 
  AND token = '5ohcjmVNTxUVZVVLMyTC9dNw/JhNAnhJWo3XNoIOJVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}