SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ca9acfd5fff1044b0b732b3767ac7a83c8e6d2614f5f5f96fd60ca02aeb321' 
  AND token = 'LuhQkdY6RAed4sCjZa2YbdB54vE7HhscjGU4/KJ8vh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}