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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6bdc4dd3ef48b9e06fb584d9277b3e2b941615930023f3e4b22be6806227d1' 
  AND token = 'ARzvxEVsxKI2hEtx7guJEZVd09FbiTXn5pJtaN9CkF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}