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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6df39c9127e5d94f9e027448f400e67ff049ef0e485ae46dd9a58a2019dc070' 
  AND token = 'yF6Wtrz1aSDsmpmGurnGkkx98jC2x22JNF83aRMl1WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}