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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0370dc0528f569db30bc1c131962dd2c9811f4c49bc1528ec856fd9c9eac49' 
  AND token = 'z2oJIzUpNsA0o8brAGHWad23tZrIgF6gTf+t7+x8d00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}